Second row Donncha Ryan is included for Munster ahead of their game with Zebre at Musgrave Park tomorrow.
Simon Zebo moves from full back to the wing while Ian Keatley is at centre and JJ Hanrahan is at out half.
Ryan's inclusion gives him the chance to impress Ireland coach Joe Schmidt ahead of next Saturdays Six Nations clash with England.
The Reds host Zebre in Musgrave Park while Connacht welcome Edinburgh to the Sportsground.
Following his start in last week's Eagles game, Dave McSharry makes a welcome return to partner Eoin Griffin in the centre for Connacht against Edinburgh tomorrow.
Craig Ronaldson shifts to outhalf where he forms the half back pairing with Kieran Marmion.
Galway-born Tiernan O'Halloran has been named to start on the left wing and features in an all-Irish qualified back line.
Up front, Connacht's highest capped player Michael Swift is brought into the second row meaning that Andrew Browne moves back to openside flanker.
Number 8 John Muldoon will captain the side.
Tonight Leinster host Dragons while Ulster welcome Scarletts to Ravenhill.
Kick off at the RDS is at 7.45 while they start at 7.15 in Belfast.
