Donnacha Ryan has been named blindside flanker for Munsters Magners league meeting with Leinster at Thomond Park while Connor Murray remains at scrum half.
Felix Jones is in at full back while Donncha O’Callaghan returns to partner Paul O’Connell in the second row.
Dennis Leamy, Marcus Horan and Paul Warwick are all on the bench.
Cian Healy and Mike Ross return to the front row for Leinster while Isaac Boss gets the nod ahead of Eoin Reddan at scrum half.
Shane Horgan will make history when he lines out for his home province for the 200th time , on the other wing Luke Fitzgerald starts while Isa Nacewa is at full back.
Internationals Heinke van der Merwe, Stan Wright, Devin Toner, Rhys Ruddock, Eoin Reddan and Fergus McFadden are named amongst a strong replacements bench.
Two Irish provinces in action this evening as Connacht host Edinburgh at 7.45 while in Ravenhill at 5 past 7 Ulster meet the Scarlets.