Munster coach Tony Mc Gahan has made 13 changes for their meeting with the Scareltts in Wales.
Only centre Lefeimi Mafi and back row Dennis Leamy keep their places, Connor Murray and Ronan O’Gara are rested while Simon Zebo and Danny Barnes are on the wings.
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Declan Cusack starts at out half while Marcus Horan is in the front row.
Connacht are the only Irish side in Magner’s League action this evening.
They host the Cardiff Blues, from 7.45pm.
Eric Elwoods side have won their last 5 home matches in the league, their best ever run in this competition.