Five Munster players will start for Ireland as Joe Schmidt has named his squad for Saturday’s meeting with Wales.
Tadhg Beirne comes into the team alongside Peter O’Mahoney, CJ Stander, Conor Murray and Keith Earls.
Niall Scannell and Dave Kilcoyne are among the replacements.
Rory Best leads out Ireland for his final Six Nations appearance.
Wales are unchanged for the game at the Principality Stadium, as they chase the Grand Slam.
Here's the Ireland team for the final round of the @SixNationsRugby Championship.#TeamOfUs #WALvIRE #ShoulderToShoulder pic.twitter.com/Y1KZDYfb7Y
— Irish Rugby (@IrishRugby) March 14, 2019
Ireland Team & Replacements (v Wales, Guinness Six Nations Championship2019, Principality Stadium, Saturday 16 March, KO 2.45pm
15 Rob Kearney (UCD/Leinster) 89 caps
14 Keith Earls (Young Munster/Munster) 76 caps
13 Garry Ringrose (UCD/Leinster) 19 caps
12 Bundee Aki (Galwegians/Connacht) 16 caps
11 Jacob Stockdale (Lurgan/Ulster) 18 caps
10 Jonathan Sexton (St Mary’s College/Leinster) 82 caps (vc)
9 Conor Murray (Garryowen/Munster) 71 caps
1 Cian Healy (Clontarf/Leinster) 87 caps
2 Rory Best (Banbridge/Ulster) 116 caps (c)
3 Tadhg Furlong (Clontarf/Leinster) 32 caps
4 Tadhg Beirne (Lansdowne/Munster) 4 caps
5 James Ryan (UCD/Leinster) 16 caps
6 Peter O’Mahony (Cork Constitution/Munster) 56 caps (vc)
7 Sean O’Brien (UCD/Leinster) 55 caps
8 CJ Stander (Shannon/Munster) 30 caps
Replacements
16 Niall Scannell (Dolphin/Munster) 13 caps
17 Dave Kilcoyne (UL Bohemians/Munster) 28 caps
18 Andrew Porter (UCD/Leinster) 13 caps
19 Quinn Roux (Galwegians/Connacht) 11 caps
20 Jack Conan (Old Belvedere/Leinster) 13 caps
21 Kieran Marmion (Galwegians/Connacht) 24 caps
22 Jack Carty (Buccaneers/Connacht) 2 caps
23 Jordan Larmour (St Mary’s College/Leinster) 12 caps