Roche Ireland has been granted final planning permission to clear the plant at its Clarecastle site.
The works are now on track to begin this summer.
After Clare County Council gave this plan the green light in January, one appeal in relation to the application was lodged with An Bord Pleanala.
But as is the case with nearly 10% of appeals each year, it was deemed invalid – this time for matters related to the fee owed for the appeal – and as such, the Council’s decision stands.
It will allow for the pharmaceutical company to demolish all existing buildings, structures and infrastructure, on, in, over and under the 88 acre site at its operations in Clarehill, Clarecastle.
Roche believes the existing landfills contain what they describe as ‘hazardous wastes’ that would have the potential to impact the environment of the area should they remain untreated.
The Council has attached a number of conditions to the planning permission, including that there be no more than 18 truck movements into and out of the site each working hour.
Approximately 160 people will be employed on site during the works, which are scheduled to begin in the middle of this year.
Roche say the move will leave a legacy in Clarecastle of a rejuveanted brownfield site with the potential for employment creation into the future.